Introduction: The translational turn

Taking a translational turn

This month's installment of Generally Physiological takes a translational turn, discussing functional analyses of two proteins whose mutation is associated with disease (heart failure and cystic fibrosis, respectively) and the mechanism underlying the painful response to cold found in ciguatera. A tunable brake on cardiac contractility Cardiac contraction, like that of skeletal muscle, depends ...

Introduction to Translational Bioinformatics Collection

How should we define translational bioinformatics? I had to answer this question unambiguously in March 2008 when I was asked to deliver a review of ‘‘recent progress in translational bioinformatics’’ at the American Medical Informatics Association’s Summit on Translational Bioinformatics. The lecture required me to define papers in the field, and then highlight exciting progress that occurred ...

Ontologies for clinical and translational research: Introduction

Ontologies are representational artifacts that are being used in many different ways by researchers in almost every life science discipline. Their use in the annotation of both clinical and experimental data is now a common approach for knowledge representation in support of integrative translational research. When high quality ontologies are used correctly and consistently, then the descriptio...

the effect of consciousness raising (c-r) on the reduction of translational errors: a case study

در دوره های آموزش ترجمه استادان بیشتر سعی دارند دانشجویان را با انواع متون آشنا سازند، درحالی که کمتر به خطاهای مکرر آنان در متن ترجمه شده می پردازند. اهمیت تحقیق حاضر مبنی بر ارتکاب مکرر خطاهای ترجمانی حتی بعد از گذراندن دوره های تخصصی ترجمه از سوی دانشجویان است. هدف از آن تاکید بر خطاهای رایج میان دانشجویان مترجمی و کاهش این خطاها با افزایش آگاهی و هوشیاری دانشجویان از بروز آنها است.از آنجا ک...

To the Framingham data, turn, turn, turn.